The talk will focus on several phenomena related to tumor growth and spread in which mechanical aspects play a relevant role. After introducing the multiphase framework, the talk wll deal with the phenomenon of contact inhibition and then, using continuum mechanics and an individual cell-based model, with the interaction of tumour cells with the sorrounding environment and in particular with the network of
fibers that are present in most tissues. Finally, the phenomenon of cell compartimentalization is described and how its failure can initiate the invasion of the surrounding tissue and the spread of metastasis that
need to pass through basal membranes and cell lining in order to penetrate the vascular and lymphatic vessels.
It will be shown how, in order to do that, different mathematical models need to be developed and how information need to pass from microscopic to macroscopic models to have as far as possible a more
Referent: Prof. Dr. Luigi Preziosi, Politecnico di Torino, Italien
Zeit: 17:15 - 18:30 Uhr
Ort: Gebäude 48, Raum 210
Die Vorträge des Felix-Klein-Kolloquiums finden jeweils um 17.15 Uhr im Raum 210 des Mathematik-Gebäudes 48 statt. Zuvor gibt es ab 16.45 Uhr die Gelegenheit, die Sprecherin oder den Sprecher beim Kolloquiumstee in Raum 580 zu treffen.